Scientists have found a revolutionary discovery in the latest study which opens the way for two men to have offspring without a biological mother. The genetic engineering experience involved a mouse, produced without a mother, which survived up to puberty.
Previously, scientists used genetic material from two mothers to produce a sperm -free mouse, which is a simpler process compared to the reproduction of children with two sperm. The molecular biologist Zhi Kun Li led the Historical Research Use of precise engineering of stem cells. Although scientists previously created a mouse with two fathers, but this time it is remarkable for the longer health and superior health that the reproduced mouse presented.
Experience was carried out at the Chinese Academy of Sciences (CAS). This marks a significant achievement because it opens up the possibilities that homosexual couples have children. Something that seemed impossible So far, scientists will be able to reproduce a child using two sperm via genetic engineering.
Genetic engineering
This step comes after several disappointment To generate eggs from male stem cells. For an unborn child without a biological mother, substitution maternity is used as an option, but it comes with their own set of challenges. The process of creating embryos using only sperm is extremely difficult because these cells are highly specialized. Therefore, an embryonic stem cell was created to make a new embryo.
Li and his colleagues used a combination of genetic engineering techniques for the imprint of genes, including the suppression of genes, regional edition and the addition of genetic bases.
Research results
This recent research has made a breakthrough over the survival duration of mice, produced using a genetic modification. He presented superior health compared to similar animals and has not shown any apparent health problems. However, he wore various troubles was sterile.
In this study, it should be noted that half of the mouse brothers and sisters did not survive adulthood and that around 90% of the embryos were not viable. The success rate requires significant improvement before this technology can be taken into account for human application.