The 2025 NFL Playoffs are upon us and NFL Wild Card Weekend and the expanded NFL Playoff bracket have given us six games on the NFL schedule in the first round. Texans against. Chargers (-3, 42.5) and Crows against. Steelers (+9.5, 44) will take place on Saturday, while Invoices against. Broncos (+8.5, 47), Eagles against. Packers (+4.5, 45.5), and Buccaneers against. Commanders (+3, 50.5) will be played on Sunday. The action of the week ends with Rams against. Vikings (-1.5, 47.5) on Monday Night Football.
Despite playing in a rivalry game, the Ravens (-10, 43.5) are the biggest favorites in the NFL Wild Card Weekend odds. Who should you back in these games with playoff implications and how should you manage your entire NFL money line, NFL over-under and NFL versus spread picks? Before making Wild Card Weekend NFL picks and NFL playoff score predictions, you should See NFL against the spread, NFL over-under and NFL money line predictions powered by SportsLine self-learning AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI predictions and AI ratings are generated for each play. AI predictions are determined by learning statistically based on each team’s historical data, then quantitatively assessing the strength of the opponent’s defense by assigning a numerical value out of 100 called a match score.
Once a prediction is made, the AI score is generated using the prediction, comparison score, and market odds. For example, you might see an A grade on an overbet if a team faces a poor defense, if their prediction differs from the line, and if there are favorable odds.
Additionally, SportsLine AI is SportsLine’s first fully automated predictive model. It continually updates with the most recent data available and can help you spot the biggest gaps in lines. SportsLine’s AI PickBot has reached an impressive 2,131 4.5 and 5 star prop picks since the start of last season.
For the Wild Card weekend NFL bettingthe AI PickBot evaluated the NFL Odds and provided the NFL bet picks for all six games. You can only see the AI predictions for the 2025 NFL Wild Card Weekend here.
Top AI Picks from NFL Wild Card Weekend
After analyzing every game of NFL Wild Card Weekend 2025, the AI PickBot says the Rams cover comfortably as 1.5-point home underdogs against the Vikings on Monday. The Vikings had NFC North and home-field advantage in the NFC, but fell well short of expectations in a 31-9 loss to the NFC. Lions in week 18, which dropped them to a wild card spot.
Now Minnesota must travel to Los Angeles, where the Vikings already lost earlier in the season. The Rams outgained them by 110 yards in a 30-20 victory in Week 8 during a stretch in which Los Angeles won nine of 11. Matthew Stafford threw for 279 yards and four touchdowns in victory as a rookie Jared Verse had 1.5 bags and Byron Murphy recorded a late safety to help seal the victory.
As the Vikings emerge from the disappointment of the loss to Detroit, the Rams will no doubt try to follow the Lions’ plan by limiting Sam Darnold at 18 of 41 passes. The AI PickBot rates a Rams coverage as an A+ pick and also predicts an outright win of 31-22 on average. See his other NFL Wild Card Weekend score predictions and football picks at SportsLine.
How to Make NFL Wild Card Weekend Predictions
Additionally, AI PickBot has generated six highly coveted A+ picks for NFL Wild Card Weekend 2025. You should view AI PickBot’s NFL picks before making your own NFL Wild Card Weekend bets. You can only see them on SportsLine.
Who’s winning and covering every NFL Wild Card Weekend game, and which A+ picks should you target now? Visit SportsLine now to see the NFL’s top picks against the spread, above and on the money line, all sourced from the self-learning SportsLine AI PickBot that has managed 2,131 top-rated picks since the start of the last season..