Seventeen years ago, Dr. Eric Topol, cardiologist and founder of the Research Translational Institute scripps, participated in a personal and scientific mission. At the age of 53, he was no longer just interested in treating disease. Instead, he wanted to understand why some people seem to age effortlessly, remaining active and clear even in the 80s and beyond.He thought the secret could lie in their genes. But what he discovered during the next and a half decade turned this idea on his head.
The myth of genetic magic: why was DNA not the answer
In an interview with the Washington Post, Topol and his team spent more than six years decoding the DNA of 1400 people aged 80 and over, who had no major chronic diseases. They were the “super agers”, people who had apparently challenged time. But to his surprise, their genetic profiles did not have much in common. The expected model, the so-called “aging gene” was missing.So, if it was not genetics, what made these individuals defy aging in such a point? This question has become the foundation of his new book, which describes hundreds of studies on aging and health.

Studies suggest that the prolonged session can shorten the lifespan regardless of the level of activity. Systematically include physical activities to improve longevity.
What matters most?
From everything, Topol examined advanced medicine to artificial intelligence, an observation continued to climb above the rest: exercise.Yes, exercise. Not a miracle medication or expensive therapy, but a constant physical movement. Among all the lifestyle changes, exercise was the only proven intervention to slow the process of organic aging throughout the body.It was not just younger air. Science has shown that regular physical activity could literally adjust the rhythm to which the body is aging.
Strength on speed
For years, Topol had focused on cardio, such as walking, cycling and swimming. But by writing his book, he tripped on mountains of evidence on strength training. It changed his perspective and his life.

He started training in resistance in sixties and quickly became stronger than ever. It was not only the muscle – its balance improved, the posture improved and there was a new feeling of physical confidence. All from simple tools: dumbbells, resistance bands and body weight movements such as boards and slits.What stood out was the strength of grip – a simple marker – which had a strong link with long -term health and survival. It turns out that a firm handshake, it could be more than polished.
The unexpected advantages of moving with a goal
Topol’s approach is not to spend hours at the gymnasium. He formed at home, short and concentrated on training sessions a few days a week. But he added something else: balance formation. Exercises like standing on one leg or detaching themselves during balancing have helped protect against falls and support brain health.He also highlighted the advantages of being outside and remaining socially connected. Nature and friendships, two things held for acquired, have scientifically proven effects on emotional and physical health. When combined with movement, they become a powerful trifecta.
Healthspan on lifespan: living better, not just longer
The objective, as Topol explains, is not only to live longer, it is to stay healthy longer. A concept known as Healthspan. This means living free from major diseases such as cancer, heart disease and neurodegeneration as long as possible.Studies Show that healthy habits, in particular regular exercise, can add an additional ten to ten years of good health. It is almost a complete decade of life with independence, energy and vitality.Topol, now 70 years old, does not dream of immortality. He just wanted to go to the end of the 80s still active, clear and without illness. And science suggests that it is not only a vow pile, it is an achievable reality.