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Credit: UNSPLASH / CC0 public domain
Each minute, 38 people receive a diagnosis of cancer and 18 people die worldwide, according to the World Health Organization, and this should increase by 77% to 35 million in 2050. But what happens He if we could predict the risk of cancer before they even develop? Genetic tests help detect cancer early on the risk of cancer, which makes it essential for cancer prevention and control.
While the world marks the World Cancer Day on February 4, under the “unique” theme of 2025-2027, the conversation around personalized medicine and accessible screening options has never been so relevant. The new DNA -based innovations ensure that cancer care is more effective and accessible.
Early screening improves the survival rate
Cancers, like colorectal, breast and cervical cancerare very treatable if they are captured early. However, millions of people completely avoid screening, often because traditional tests are invasive, expensive, annoying or intimidating. For Colorectal cancer (CRC), one of the most avoidable but the drugged cancers, the figures are clear: if they are captured in its first step, the five -year survival rate is greater than 90%. But when diagnosed late, survival falls at only 14%.
Coloscopies, the gold stallion for CRC screening, require fasting, laxative preparation and a visit to the hospital, which can be sufficient for someone to reject it indefinitely. Complicated preparation allows people to repel it indefinitely. In many cases, people simply do not realize that they are at risk until the symptoms appear – how much more difficult treatment is.
Screening must be accessible
Traditional cancer screening methods are not only uncomfortable – they are also a major reason why screening rates remain low in the world. To attack these obstacles to early projectionDNA -based stool tests as an innovative approach, offer an easier, non -invasive and promising alternative that can take cancer early.
Last year, we covered the history of colorectal cancer of Uncle Ren in Hangzhou, China. Another participant in the same public health program, Uncle Jiang, had never been screened for CRC before. When his test results came back positive for abnormal biomarkers, he immediately feared the worst. “I thought it was over. Maybe it was already cancer at a late stadium,” he recalls.
With the help of his family doctor, he went to a specialized hospital for a colonoscopy. At night before the procedure, however, turned out to be almost stressful as waiting for the results.
He remembers going to the toilet every fifteen minutes. “If you ask for a colonoscopy at the beginning, even if it is a free test, I will probably not choose it. It will not stop all night.” He said reluctantly. Fortunately, colonoscopy revealed that it had a tubular adenoma, a precancerous condition and six polyps were removed, eliminating its health risks.
The story of Uncle Jiang is not unique. Millions of people avoid screening due to drawbacks or fear, but when non -invasive options such as stool DNA tests become available, more people are tested, more cases are taken early and other lives are saved.
The non -invasive method improves the screening rate
To approach low screening rates, researchers and health care providers are turning to DNA -based stool tests, a revolutionary alternative to traditional colonoscopy. “The best screening method is that the patient accepts and adheres because it is the method that will be really beneficial to them,” said Professor Varut Lohsiriwat, teacher of surgery in the general surgery division (colorectal surgery section) From the Siriraj hospital, the University of Mahidol underlined in an interview.
Tests such as the BGI BGI Genomics DNA DNA DNA test provide an pain alternative to colonoscopy for early CRC detection. THE recent study Led by Professor Varut Lohsiriwat’s team in Thailand revealed that DNA DNA tests are very effective, offering a precise and accessible alternative to the invasive screening of the Thai population. As a reliable alternative to colonoscopy, multitartaux DNA tests can greatly improve accessibility and compliance rate for the general public in the recommended target screening group.
A study revealed that the availability of colorectal cancer screening in multiple stools (MT-SDNA) has led to a compliance with high screening of 88% and the compliance of diagnostic colonoscopy on positive MT-SDNA cases 96% , published in World gastroenterol newspaper In 2017. By making early and accessible early detection, more people will be detected – and fewer cases will go to the potentially fatal stages.
Prevention begins small
Although genetic screening helps detect cancer early, healthy lifestyle choices remain a crucial defense against cancer development in the first place. Up to 40% of diagnosed cancer and almost half of cancer deaths could be prevented through lifestyle changesAccording to a study published in CA: a cancer newspaper for clinicians.
Another study, published in Borders in molecular biosciences In 2022, shows that high intensity exercise can delete tumor growth By influencing the keys to cancer genes. The researcher used high -speed sequencing to identify the genes expressed differentially (for example, TRIM63, FOS, COL1A1, Six2) regulated by this exercise, which had a negative impact on the development of colorectal cancer. These effects have been confirmed in vitro.
The suppressive effects of the exercise tumor depend on the type, intensity, frequency and type of cancer, requiring personalized exercise interventions. This study used mice subjected to high intensity aerobic exercise (90% of the maximum heart rate) to highlight the importance of preventive exercise and a lifestyle centered in exercise. THE World Cancer Research Fund (WCRF) Also reported that diets rich in vegetables, whole grains and lean proteins considerably reduce the risk of cancer, while smoking alone is responsible for one out of five out of five worldwide.
Prevention should not mean drastic lifestyle revisions. Small constant changes – more movement, a healthier diet and a reduction in harmful habits – can make a big difference in reducing the risk of cancer over time.
While World Cancer Day 2025 is approaching, it is a reminder that even if each cancer journey is different, we all share the same objective: the reduction in the impact of cancer. Cancer is not just playing, but with better screening, smarter prevention and early action, we can change the future.
Supplied by BGI Genomics
Quote: Early screening and lifestyle changes are essential to prevent cancer cases (2025, February 7) recovered on February 7, 2025 from https://medicalxpress.com/News/2025-02-early-Screening -lifestyle-ky-cancer.html
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