A new study Published in the journal Nature Medicine have found that in terms of longevity, your lifestyle and your environment have more than your genes.
Research, led by researchers from Oxford Population Health, examined in -depth data of more than 490,000 people in British biobanque, including their detailed medical stories and their genetic sequencing, as well as their environmental exhibitions.
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The researchers then explored the influence of genetic and environmental factors on proteomic mortality and aging.
Do you want a longer life? The lifestyle is more important than genetics.
Thanks to research, “we can obtain an estimate of the speed or slowness that each participant is aging biologically in relation to their chronological age”, ” The said main author Austin ArgeieriResearcher at the General Hospital of Massachusetts.
“This is called” the proteomic age gap “, because it is the gap between the years between the age predicted by proteins and the chronological age”, continued Argentierieri. “(It is) a very strong predictor of mortality … (and) it is also strongly associated with many significant aging features such as fragility and cognitive function.”
To further explore the cause of an individual’s proteomic age gap, researchers have examined both environmental and behavioral exhibitions, including income, matrimonial state, food, exercise habits, neighborhood, etc.
On the other hand, they also took into account the genomes and genetic markers of individuals for various diseases.
The results?
“The environmental factors explained 17% of the variation in the risk of death, against less than 2% explained by the genetic predisposition”, ” The press release reads.
In addition, smoking, socioeconomic status, physical activity and living conditions were the most impactful environmental factors on mortality and biological aging.
“Our research demonstrates the deep impact of the health of exhibitions that can be modified either by individuals or by policies aimed at improving socio-economic conditions, reducing smoking or promoting physical activity,” said Professor Cornelia Van Duijn, professor of Oxford Epidemiology Health and the main author of the Journal.
“While genes play a key role in brain conditions and certain cancers, our results highlight the opportunities to mitigate the risks of chronic lung, heart and liver disease, which are causes of disability and death on a global scale.”
“Our approach to the exhibition has enabled us to quantify the relative contributions of the environment and from genetics to aging, providing the most complete overview to date of environmental factors and lifestyle stimulating aging and premature death,” added Argerieri.
“These results highlight the potential advantages of concentration of concentration on our environments, our socioeconomic contexts and our behaviors for the prevention of many diseases related to premature age and death.”