The 2025 College Football Playoff will continue with the semifinals when No. 6 Penn State Nittany Lions will face number 7 Notre Dame fighting the Irish at the 2025 Orange Bowl on Thursday. The Fighting Irish are 13-1 this season and own the nation’s longest winning streak heading into the semifinals (12 games), while the Nittany Lions are 13-2. Notre Dame beat Indiana and Georgia en route to the final four, while Penn State beat SMU and Boise State. Star Penn State defensive end Abdul Carter (arm) will be a game-time decision, according to head coach James Franklin.
Kickoff is set for 7:30 p.m. ET at Hard Rock Stadium in Miami Gardens, Florida. The Fighting Irish are 1.5-point favorites in the latest Notre Dame vs. Penn State odds from the SportsLine consensus, while the over/under for the point total. The score obtained is 45.5. Notre Dame is 12-2 ATS this season, while Penn State is 8-7 ATS. Before making any choices between Notre Dame and Penn State, you need to see the College Football Playoff predictions and betting tips from SportsLine’s Jimmie Kaylor.
Kaylor is an NFL, college football and DFS expert for SportsLine, covering the NFL and college football for nearly a decade as a member of the Pro Football Writers of America. His experience as a former All-American and NFL college football player gives him a unique perspective when it comes to building his fantasy teams and locking in his betting picks. He has his finger on the pulse of the college football landscape and has won big on sports betting apps for two years.
Kaylor destroyed the sports betting in college football over the past two seasons, posting a record of 232-150-7 since the first week of the 2023 season. His futures picks for college football in 2024 included Travis Hunter winning the Heisman Trophy with odds of 40-1, bringing his net profit to 112.07 units ($11,206.50 for a $100 bettor) since joining SportsLine as as an expert in 2023.
All of his picks have been featured on his SportsLine Experts page or in his weekly byline articles. Anyone who followed his bet the choices could be very high.
Now Kaylor called Notre Dame vs. Penn State at the Orange Bowl 2025 and has just revealed his picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds And college football betting lines for Penn State vs. Notre Dame:
- Notre Dame vs. Penn State Spread: Notre Dame -1.5
- Notre Dame vs. Penn State plus/minus: 45.5 points
- Notre Dame vs. Penn State Money Line: Notre Dame -110, Penn State -110
- Notre Dame vs. Penn State Pick: See the picks on SportsLine
- Notre Dame vs. Penn State streaming: FuboTV (try for free)
Notre Dame vs. Penn State Expert Predictions
For the 2025 Orange Bowl, Kaylor is under the total (45.5), although it is eight points lower than the other College Football Playoff semifinal between Texas and Ohio State. Both of these defenses rank among the top 10 in the nation in defensive scoring, with Notre Dame allowing 13.6 points per game (second in the nation) and Penn State allowing 15.8 points per game (seventh).
The Fighting Irish had to overcome the loss of their best defensive lineman (Rylie Mills) in the quarterfinals, but they still managed to put relentless pressure on Georgia. Notre Dame had four sacks and nine tackles for loss in the victory. Meanwhile, Penn State has one of the nation’s best rushers in Abdul Carter (22 tackles for loss and 11 sacks) and just held Heisman Trophy finalist Ashton Jeanty to 3.5 yards per carry in its quarterfinal victory over Boise State.
“Both teams are elite defensively, and I see this game turning into a brawl. Notre Dame has dominated the line of scrimmage all season, and that continued against Georgia in their quarterfinal game of the CFP last week. Penn State should make life difficult for Notre Dame offense,” Kaylor told SportsLine. See which way to go back here.
How to make choices between Penn State and Notre Dame
In addition to going Under, Kaylor discovered a critical He shares just what it is and which side to support, on SportsLine.
So who wins Notre Dame against Penn State in the Orange Bowl, and what critical X-factor makes one side of the spread a must-win? Visit SportsLine now to see which side of the spread to jump to, all from the expert who has profited $11,207 from $100 college football bettors since Week 1 of the 2023 season.and find out.